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  1. Scientific AmericanKaigham J. Gabriel6 min
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    Scientific American
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    • deephdave
      Top reader of all timeScoutScribe
      4 years ago

      This slowing pace and rising cost of R&D has recently been coined Eroom's law, so named because it's the opposite to Moore's law from microelectronics, whereby computing power doubles and cost is halved roughly every 18 months. There are many explanations given for why drug discovery has followed Eroom's law, from cautious regulators to increasing overall R&D costs. But one of the biggest areas holding back progress is inefficiency in the preclinical, animal testing phase of the drug-discovery process. Only one in 10 drugs that enter human clinical trials reach the market after preclinical success.

    • SEnkey4 years ago

      It's scary to think what promising meds were scrapped because they didn't work in animal testing, when they might have worked on humans.